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Dactolisib, MedChemExpress

Product Code. 16467846
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Product Code. 16467846 Supplier Medchem Express Supplier No. HY50673

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Description

MedChemExpress Dactolisib (BEZ235) is an orally active and dual pan-class I PI3K and mTOR kinase inhibitor with IC50s of 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR, respectively. Dactolisib (BEZ235) inhibits both mTORC1 and mTORC2.

Dactolisib (BEZ235) is an orally active and dual pan-class I PI3K and mTOR kinase inhibitor with IC50s of 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR, respectively. Dactolisib (BEZ235) inhibits both mTORC1 and mTORC2.

Specifications

Chemical Name or Material Dactolisib
CAS 915019-65-7
Color White
Purity Grade Notes Research
Molecular Formula C30H23N5O
Quantity 100 mg
Synonym BEZ235 NVP-BEZ235
Solubility Information 5% TFA : 8.33 mg/mL (17.74 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 5 mg/mL (10.65 mM; ultrasonic and warming and heat to 60°C) ∣DMF : 2 mg/mL (4.26 mM; Need ultrasonic)
SMILES CN(C1=C2C3=CC(C4=CC5=CC=CC=C5N=C4)=CC=C3N=C1)C(N2C6=CC=C(C=C6)C(C)(C#N)C)=O
Molecular Weight (g/mol) 469.54
Formula Weight 469.54
Percent Purity 96.41%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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