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  5. MP Biomedicals™ Collagenase Type I from Clostridium histolyticum

MP Biomedicals™ Collagenase Type I from Clostridium histolyticum

Product Code. 11480972 Shop All MP Biomedicals Products
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Quantity:
500 mg
1 g
Unit Size:
1g
500mg
This item is not returnable. View return policy

Product Code. 11480972

Brand: MP Biomedicals™ 02195109.5

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This item is not returnable. View return policy

Description

For the preparation of isolated cell suspensions

The collagenase product is a mixture of enzymes secreted by C. histolyticum, with different products differentiated by the relative ratios of the 10-18 components found in the secreted enzymes. The main components are two collagenases, clostripain, and a neutral protease. The synergistic action of these enzymes degrade collagen and other intracellular material. The action of both collagenase enzymes and the neutral protease is necessary for effective release of cells from tissue. Various types of collagen are the natural substrates for collagenase.

Unit Definition: One unit will liberate peptides from collagen equivalent in ninhydrin color to 1.0μmol of L-leucine in 5 hr. at pH 7.4 and 37°C in presence of calcium ions. Contains clostripain, neutral protease and trypsin activities.

TRUSTED_SUSTAINABILITY

Specifications

Concentration >125 U/mg
Color Brown
For Use With (Application) Preparation of isolated cell suspensions
Content And Storage Store at 4°C. Desiccate.
Quantity 500 mg
Product Type Collagenase Type I
Form Lyophilized

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • Collagenase, Type I
 Signal Word
  • Danger
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Respiratory sensitiser Category 1
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H319-Causes serious eye irritation.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Collagenase
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