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Ceritinib, MedChemExpress

Product Code. 16481186
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Product Code. 16481186

Brand: Medchem Express HY15656

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Description

MedChemExpress Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency.

Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency.

Specifications

Chemical Name or Material Ceritinib
CAS 1032900-25-6
Color White
Purity Grade Notes Research
Molecular Formula C28H36ClN5O3S
Quantity 200 mg
Synonym LDK378
Solubility Information DMSO : 5.6 mg/mL (10.03 mM; Need ultrasonic) ∣Ethanol : ≥ 3.33 mg/mL (5.97 mM)
SMILES CC(C)OC1=CC(C2CCNCC2)=C(C)C=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3
Molecular Weight (g/mol) 558.14
Formula Weight 558.14
Percent Purity 97.21%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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