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Bumetanide, MedChemExpress

Product Code. 16499837
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Product Code. 16499837 Supplier Medchem Express Supplier No. HY17468

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MedChemExpress Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively.

Bumetanide (Ro 10-6338

Specifications

Chemical Name or Material Bumetanide
CAS 28395-03-1
Color White
Purity Grade Notes Research
Molecular Formula C17H20N2O5S
Quantity 5 g
Synonym Ro 10-6338 PF 1593
Solubility Information DMSO : 100 mg/mL (274.41 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.27 mM; Need ultrasonic)
SMILES O=C(O)C1=CC(NCCCC)=C(OC2=CC=CC=C2)C(S(=O)(N)=O)=C1
Molecular Weight (g/mol) 364.42
Formula Weight 364.42
Percent Purity 99.31%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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