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Tocris Bioscience™ Bosutinib

Product Code. 18025112
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18025112

Brand: Tocris Bioscience™ 4361/50

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This item is not returnable. View return policy

Description

Dual Src-Abl inhibitor; antiproliferative

Dual inhibitor of Abl and Src kinases (IC50 = 1.2 nM for Src in an enzymatic assay). Displays antiproliferative activity against chronic myelogenous leukemia (CML) cells and decreases the motility and invasion of breast cancer cell lines. Also exhibits potent antiproliferative activity in anchorage-independent, Src-transformed rat fibroblasts (IC50 = 100 nM). Displays selectivity for Src over non-Src family kinases such as growth factor receptor tyrosine kinases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 380843-75-4
Molecular Formula C26H29Cl2N5O3

Specifications

Quantity 50 mg
Formula Weight 530.45
Purity >99%
Molecular Weight (g/mol) 530.45
Chemical Name or Material Bosutinib
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