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BMS-309403, MedChemExpress

Product Code. 16493628
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Product Code. 16493628 Supplier Medchem Express Supplier No. HY101903

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MedChemExpress BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively.

BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.

Specifications

Chemical Name or Material BMS-309403
CAS 300657-03-8
Color White
Purity Grade Notes Research
Molecular Formula C31H26N2O3
Quantity 10 mg
Solubility Information DMSO : 100 mg/mL (210.73 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
Molecular Weight (g/mol) 474.55
Formula Weight 474.55
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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