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Tocris Bioscience™ Bexarotene
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Product Code. 18731348
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Product Code. 18731348 Supplier Tocris Bioscience™ Supplier No. 5819/10

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Description

Potent and selective RXR agonist

Bexarotene is a potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXRβ, RXRγ and RXRα, respectively). Exhibits >300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro, and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.
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Specifications

Chemical Name or Material 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
CAS 153559-49-0
Synonym LGD 1069
Quantity 10 mg
Target Retinoid X Receptor Agonists
Molecular Formula C24H28O2
Formula Weight 348.48
Purity >99%
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