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Tocris Bioscience™ Bexarotene
Potent and selective RXR agonist
Brand: Tocris Bioscience™ 5819/10
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Description
Bexarotene is a potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXRβ, RXRγ and RXRα, respectively). Exhibits >300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro, and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.Specifications
| 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid | |
| 153559-49-0 | |
| LGD 1069 | |
| 10 mg |
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