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Begacestat, MedChemExpress

Product Code. 16441399
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Product Code. 16441399 Supplier Medchem Express Supplier No. HY14175

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Description

MedChemExpress Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease.

Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease.

Specifications

Chemical Name or Material Begacestat
CAS 769169-27-9
Color White
Purity Grade Notes Research
Molecular Formula C9H8ClF6NO3S2
Quantity 1 mg
Synonym GSI-953
Solubility Information DMSO : 50 mg/mL (127.64 mM; Need ultrasonic)
SMILES FC(F)(F)C([C@H](NS(=O)(C1=CC=C(Cl)S1)=O)CO)C(F)(F)F
Molecular Weight (g/mol) 391.74
Formula Weight 391.74
Percent Purity 99.0%
Grade Research
Physical Form Powder
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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