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BAY 11-7082, MedChemExpress

Product Code. 16476186
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Product Code. 16476186 Supplier Medchem Express Supplier No. HY13453

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Description

MedChemExpress BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor.

BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells.

Specifications

Chemical Name or Material BAY 11-7082
CAS 19542-67-7
Color White
Purity Grade Notes Research
Molecular Formula C10H9NO2S
Quantity 100 mg
Synonym BAY 11-7821
Solubility Information DMSO : ≥ 100 mg/mL (482.51 mM)
SMILES N#C/C=C/S(=O)(C1=CC=C(C)C=C1)=O
Molecular Weight (g/mol) 207.25
Formula Weight 207.25
Percent Purity 99.28%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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