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AV-412, MedChemExpress

Product Code. p-200100846
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16473848 10 mg 10mg
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Product Code. 16473848 Supplier Medchem Express Supplier No. HY10346

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Description

MedChemExpress AV-412 (MP412) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

AV-412 (MP412) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

Specifications

Chemical Name or Material AV-412
CAS 451493-31-5
Color Yellow
Purity Grade Notes Research
Molecular Formula C41H44ClFN6O7S2
Quantity 10 mg
Synonym MP412
Solubility Information DMSO : ≥ 28 mg/mL (32.89 mM)
SMILES O=S(C1=CC=C(C)C=C1)(O)=O.C=CC(NC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2C#CC(N5CCN(C)CC5)(C)C)=O.O=S(C6=CC=C(C)C=C6)(O)=O
Molecular Weight (g/mol) 851.41
Formula Weight 851.41
Percent Purity 98.1%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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