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Atiprimod dihydrochloride, Tocris Bioscience™
Description
JAK2 inhibitor (IC50 = 397 nM). Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.
Specifications
Specifications
| CAS | 130065-61-1 |
| Molecular Formula | C22H46Cl2N2 |
| Quantity | 10 mg |
| Synonym | atiprimod dihydrochloride, atiprimod dihydrochloride usan, atiprimod hcl, atiprimod hydrochloride, 2-3-diethylamino propyl-8,8-dipropyl-2-azaspiro 4.5 decane dihydrochloride, 2-azaspiro 4.5 decane-2-propanamine n,n-diethyl-8,8-dipropyl-, dihydrochloride, 2-azaspiro 4.5 decane-2-propanamine, n,n-diethyl-8,8-dipropyl-, dihydrochloride, 3-8,8-dipropyl-3-azaspiro 4.5 decan-3-yl-n,n-diethylpropan-1-amine dihydrochloride, n,n-diethyl-8,8-dipropyl-2-azaspiro 4.5 decane-2-propanamine dihydrochloride |
| InChI Key | MOUZYBYTICOTFQ-UHFFFAOYSA-N |
| SMILES | CCCC1(CCC2(CC1)CCN(C2)CCCN(CC)CC)CCC.Cl.Cl |
| IUPAC Name | 3-(8,8-dipropyl-2-azaspiro[4.5]decan-2-yl)-N,N-diethylpropan-1-amine;dihydrochloride |
| Molecular Weight (g/mol) | 409.524 |
| PubChem CID | 166556 |
| Formula Weight | 409.52 |
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