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  8. ARQ 531, MedChemExpress

ARQ 531, MedChemExpress

Product Code. 16495446
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Product Code. 16495446 Supplier Medchem Express Supplier No. HY112215

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Description

MedChemExpress ARQ 531 (MK-1026) is a reversible non-covalent and orally active inhibitor of Bruton’s Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.

ARQ 531 (MK-1026) is a reversible non-covalent and orally active inhibitor of Bruton’s Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.

Specifications

Chemical Name or Material ARQ 531
CAS 2095393-15-8
Color Off-White
Purity Grade Notes Research
Molecular Formula C25H23ClN4O4
Quantity 100 mg
Synonym MK-1026
Solubility Information DMSO : ≥ 50 mg/mL (104.40 mM)
SMILES O=C(C1=C(C=C(OC2=CC=CC=C2)C=C1)Cl)C3=CNC4=NC=NC(N[C@@H]5CC[C@@H](CO)OC5)=C34
Molecular Weight (g/mol) 478.93
Formula Weight 478.93
Percent Purity 98.52%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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