missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Lipids and Lipid Derivatives
  5. Fatty acid conjugates
  6. Arachidonic acid, ≥98%, MP Biomedicals™

Arachidonic acid, ≥98%, MP Biomedicals™

Product Code. 11473211 Shop All MP Biomedicals Products
Change view
Click to view available options
Quantity:
10 mg
50 mg
100 mg
0.5 g
Unit Size:
100mg
10mg
500mg
50mg
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
11473211 10 mg 10mg
11483211 50 mg 50mg
11493211 100 mg 100mg
11403221 0.5 g 500mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
This item is not returnable. View return policy
Product Code. 11473211 Supplier MP Biomedicals Supplier No. 0215038410

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Arachidonic Acid, >98%, Clear, Colorless Liquid, essential fatty acid, and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

  • Occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and is a constituent of animal phosphatides.
  • Arachidonic acid (AA) is an unsaturated ω6 fatty acid constituent of the phospholipids of cell membranes.
  • Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation.
  • AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via cytochrome p450-catalyzed metabolism.
  • AA and its metabolites play important roles in a variety of biological processes, including signal transduction, smooth muscle contraction, chemotaxis, cell proliferation and differentiation, and apoptosis.
  • AA has been demonstrated to bind to the a subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs).
  • Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.
  • Arachidonic acid stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules (collagen IV and vitronectin).
  • Arachidonic acid plays a key role in cellular regulation and is controlled through multiple interconnected pathways.
  • Changes in arachidonic acid levels correspond to the synthesis of eicosanoids resulting from receptor-stimulated lipid hydrolysis.
  • It activates protein kinase C.
  • Arachidonic acid serves as a precursor to numerous eicosanoids as well as other bioactive molecules.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 506-32-1
Molecular Formula C20H32O2
MDL Number MFCD00004417
PubChem CID 444899
ChEBI CHEBI:15843
IUPAC Name (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
SMILES CCCCCC=CCC=CCC=CCC=CCCCC(=O)O

Specifications

Color Colorless
Density 0.922g/mL
Assay Percent Range >98%
Quantity 10 mg
Synonym arachidonic acid, arachidonate, immunocytophyte, all-z-5,8,11,14-eicosatetraenoic acid, 5z,8z,11z,14z-icosa-5,8,11,14-tetraenoic acid, cis-5,8,11,14-eicosatetraenoic acid, 5,8,11,14-eicosatetraenoic acid, all-z, all-cis-5,8,11,14-eicosatetraenoic acid, unii-27yg812j1i, 5z,8z,11z,14z-eicosatetraenoic acid
InChI Key YZXBAPSDXZZRGB-DOFZRALJSA-N
Molecular Weight (g/mol) 304.474
Formula Weight 304.5
Physical Form Liquid
Chemical Name or Material Arachidonic acid
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.