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Tocris Bioscience™ AP 24534

Product Code. 18075312
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Quantity:
10 mg
Unit Size:
10mg
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18075312 10 mg 10mg
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Product Code. 18075312 Supplier Tocris Bioscience™ Supplier No. 4274/10

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313.60 EUR valid until 2026-03-31
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Description

Potent multi-kinase and pan-Bcr-Abl inhibitor

Potent multi-kinase and pan-Bcr-Abl inhibitor. Displays potent activity against cell lines expressing native Bcr-Abl or Bcr-AblT3151 (IC50 values are 0.37 and 2.0 nM respectively); also inhibits other Abl kinase domain mutants at nanomolar potencies. Exhibits inhibitory activity against PDGFRα, c-Src and c-Kit (IC50 values are 1.1, 5.4 and 12.5 nM respectively); potently inhibits FGFR and VEGFR family kinases. Orally active. Identified as targeting human host proteins that interact with SARS-CoV-2.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 943319-70-8
Molecular Formula C29H27F3N6O

Specifications

Quantity 10 mg
Formula Weight 532.56
Purity >98%
Molecular Weight (g/mol) 532.571
Chemical Name or Material AP 24534
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