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Phospho-SMAD3 (Ser208) Polyclonal Antibody, Invitrogen™

Product Code. 15555441
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Quantity:
100 μg
Unit Size:
100µg
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15555441 100 μg 100µg
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Product Code. 15555441 Supplier Invitrogen Supplier No. PA538521

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Description

Rabbit Polyclonal Antibody

Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of GF beta/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF beta and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF beta signaling by interfering with TGF beta-mediated phosphorylation of other Smad proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SMAD3 (Ser208)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SMAD3
Gene Accession No. P84022, Q8BUN5, P84025
Gene Alias Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3, SMAD3, MADH3
Gene Symbols SMAD3
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Ser208 (N-L-SP-P-N)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17127, 25631, 4088
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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