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Phospho-Rb (Ser795) Polyclonal Antibody, Invitrogen™

Product Code. 15555071
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100 μg
Unit Size:
100µg
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15555071 100 μg 100µg
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Product Code. 15555071 Supplier Invitrogen Supplier No. PA538146

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Rabbit Polyclonal Antibody

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Rb (Ser795)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RB1
Gene Accession No. P06400, P13405, P33568
Gene Alias P105-RB, PP105, PP110, RB-1, RB1, Retinoblastoma-associated protein
Gene Symbols RB1
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human Rb around the phosphorylation site of Ser795 (P-S-SP-P-L)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19645, 24708, 5925
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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