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Invitrogen™ Phospho-NeuroD1 (Ser274) Polyclonal Antibody

Product Code. 15504601
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Quantity:
100 μL
Unit Size:
100µL
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15504601 100 μL 100µL
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Product Code. 15504601 Supplier Invitrogen™ Supplier No. PA537657

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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is HeLa cells.

NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NeuroD1 (Ser274)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NEUROD1
Gene Accession No. Q13562, Q60867, Q64289
Gene Alias Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; beta-cell E-box transcriptional activator 2; BHF1; BHF-1; bHLHa3; Class A basic helix-loop-helix protein 3; MODY6; neuro d1; Neurod; Neurod1; neurogenic differentiation 1; neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1
Gene Symbols NEUROD1
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of Serine 274(P-L-S(p)-P-P) derived from Human Neuro D.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18012, 29458, 4760
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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