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CD23 Mouse anti-Human, PE, Clone: 138628, Invitrogen™

Product Code. 15523242 Shop All Thermo Scientific Products
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100 Tests
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Product Code. 15523242 Supplier Invitrogen Supplier No. MA523549

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Description

Mouse Monoclonal Antibody

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD23
Applications Flow Cytometry
Classification Monoclonal
Clone 138628
Conjugate PE
Formulation Buffered saline solution with BSA and 0.1% sodium azide
Gene FCER2
Gene Accession No. P06734
Gene Alias CD23, CD23A, CLEC4J, FCE2, IGEBF, BLAST-2, C-type lectin domain family 4, member J, CD23 antigen, fc-epsilon-RII, immunoglobulin E-binding factor, low affinity immunoglobulin epsilon Fc receptor, lymphocyte IgE receptor
Gene Symbols FCER2
Host Species Mouse
Immunogen Human CD23
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2208
Target Species Human
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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