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Andropanolide, MedChemExpress

Product Code. 16431658
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Product Code. 16431658 Supplier Medchem Express Supplier No. HYN1912

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Description

MedChemExpress Andrographolide (Andro) is a small antagonist for NF-κB activation by covalent modifying reduced cysteine 62 of p50.

Andrographolide is a bicyclic diterpenoid lactone mainly produced from the plant Andrographis (Andrographis paniculate). Andrographolide suppresses the activation of NF-κB in stimulated endothelial cells, which reduces the expression of cell adhesion molecule E-selectin and prevents E-selectin-mediated leukocyte adhesion, but has no effect on IκBα degradation, p50 and p65 nuclear translocation.

Specifications

Chemical Name or Material Andropanolide
CAS 869807-57-8
Color White
Purity Grade Notes Research
Molecular Formula C20H30O5
Quantity 5 mg
SMILES O=C1OC[C@@H](O)/C1=C/C[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C
Molecular Weight (g/mol) 350.45
Formula Weight 350.45
Percent Purity 98.78%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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