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Aflatoxin B1, crystalline, Thermo Scientific Chemicals

Product Code. p-50973 Shop All Thermo Scientific Chemicals Products
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50mg
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Produktkod. 10593011

Brand: Thermo Scientific Acros 227340010

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Beskrivning

Aflatoxin B1, crystalline, CAS # 1162-65-8, is a member of a group of mycotoxins presenting potent hepatotoxic and carcinogenic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Aflatoxin B1 (AFB1) is a member of a group of mycotoxins produced by Aspergillus flavus, and Aspergillus parasiticus showing carcinogenic activities
• AFB1 can induce the transversion of G to T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in a mutation and promoting the carcinogenic process

Applications

• Aflatoxin B1 shows teratogenic activity
• It is a CYP1A2, CYP2A6, CYP2D6, and CYP3A substrate and can be used to study the CYP family in in vitro and in vivo studies.
• It can cause immunosuppression in animal models.

TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 1162-65-8
Molecular Formula C17H12O6
Molecular Weight (g/mol) 312.28
MDL Number MFCD00869647
InChI Key OQIQSTLJSLGHID-UHFFFAOYNA-N
Synonym ccris 12, aflatoxin b, 2,3,6aalpha,9aalpha-tetrahydro-4-methoxycyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, aflatoxin-b1, unii-9n2n2y55mh, afb1, 1h,11h-cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-4-methoxy-, 6ar,9as, cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, 6ar,9as, aflatoxin b1, cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy
PubChem CID 186907
ChEBI CHEBI:2504
IUPAC Name 11-methoxy-6,8,19-trioxapentacyclo[10.7.0.0²,⁹.0³,⁷.0¹³,¹⁷]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione
SMILES COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C2C3C=COC3OC2=C1

Specifikationer

Packaging Glass bottle
Quantity 1 mg
Merck Index 15, 171
Formula Weight 312.27
Chemical Name or Material Aflatoxin B1

Säkerhet och hantering

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Produktbeteckning
  • Aflatoxin B1
 Signalord
  • Danger
 Riskkategorier
  • Acute toxicity Category 1
  • Acute toxicity Category 2
  • Carcinogenicity Category 1A
 Faroangivelser
  • H300-Fatal if swallowed.
  • H310-Fatal in contact with skin.
  • H330-Fatal if inhaled.
  • H350-May cause cancer.
 Skyddsangivelse
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P310-Immediately call a POISON CENTER/doctor/.
  • P361-Take off immediately all contaminated clothing.
 Kompletterande information
  • MIXTURE LIST-Contains : Aflatoxine AFB1
SDS

RUO – Research Use Only

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