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AF-353, MedChemExpress

Product Code. 16486078
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16486078 10 mg 10mg
16472217 50 mg 50mg
16428687 5 mg 5mg
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Product Code. 16486078 Supplier Medchem Express Supplier No. HY14483

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Description

MedChemExpress AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3.

AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3.

Specifications

Chemical Name or Material AF-353
CAS 865305-30-2
Color Brown
Purity Grade Notes Research
Molecular Formula C14H17IN4O2
Quantity 10 mg
Synonym Ro-4
Solubility Information DMSO : 100 mg/mL (249.87 mM; Need ultrasonic)
SMILES CC(C)C1=C(OC2=CN=C(N)N=C2N)C=C(I)C(OC)=C1
Molecular Weight (g/mol) 400.21
Formula Weight 400.21
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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