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Adapalene, MedChemExpress

Product Code. 16442006
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Product Code. 16442006 Supplier Medchem Express Supplier No. HYB0091

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Description

MedChemExpress Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity.

Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity.

Specifications

Chemical Name or Material Adapalene
CAS 106685-40-9
Color White
Purity Grade Notes Research
Molecular Formula C28H28O3
Quantity 500 mg
Synonym CD271
Solubility Information DMSO : 20 mg/mL (48.48 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES COC1=C(C23CC4CC(C3)CC(C2)C4)C=C(C5=CC6=C(C=C(C(O)=O)C=C6)C=C5)C=C1
Molecular Weight (g/mol) 412.52
Formula Weight 412.52
Percent Purity 97.0%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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