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TOKU-E™ Actinomycin D ReadyMade™ Solution

Product Code. 30044027
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Quantity:
10 x 1 mL
Unit Size:
10mL
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30044027 10 x 1 mL 10mL
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Product Code. 30044027 Supplier TOKU-E™ Supplier No. A22710x1ML
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Estimated Shipment: 30-09-2026
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Description

Actinomycin D ReadyMade™ Solution is provided as a filter-sterilized solution of Actinomycin D in DMSO.

  • CAS Number: 50-76-0
  • Molecular Formula: C62H86N12O16
  • Molecular Weight: 1255.42 g/mol
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Streptomyces sp.
  • Spectrum: Actinomycin D has an inhibitory effect on Gram-positive, Gram-negative bacteria and some fungi. However, its toxicity precludes its use for infectious diseases
  • Mechanism of Action: Actinomycin is a cyclic polypeptide-containing antibiotic that binds to DNA and inhibits RNA polymerase activity

As Actinomycin can bind DNA duplexes, it can also interfere with DNA replication, although other chemicals such as hydroxyurea are better suited for use in the laboratory as inhibitors of DNA synthesis. Actinomycin D and its fluorescent derivative,7-aminoactinomycin D (7-AAD), are used as stains in microscopy and flow cytometry applications. The affinity of these stains/compounds for GC-rich regions of DNA strands makes them excellent markers for DNA. 7-AAD binds to single stranded DNA; therefore, it is a useful tool in determining apoptosis and distinguishing between living and dead cells.

Spécification

CAS 50-76-0
Certifications/Compliance Purity >95.0%
Chemical Name or Material Actinomycin D
Color Clear to Dark orange
Content And Storage -20°C, Protect from light
Description Actinomycin ReadyMade™ Solution 2 mg/mL in DMSO, Sterile Filtered
Concentration 2.0 to 2.1 mg/mL
Form Liquid
Product Type Antibiotic
Sterility Sterile
Sterilization Method Sterile-filtered
With Additives None
Without Additives None
Formulation Liquid, 0.2% in Dimethyl Sulfoxide
For Use With (Application) Microbiology, Plant Biology, Eucaryotic Cell Culture and Cancer Applications
Manufacturing Quality 1 mL
Product Line ReadyMade™ Solutions
Purity or Quality Grade >95.0%
Quantity 10 x 1 mL
Shipping Condition Ice Pack
Source Streptomyces sp.
Species Bacteria
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