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Tocris Bioscience™ AC 265347
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Product Code. p-7114666
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18738239

Brand: Tocris Bioscience™ 6165/10

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Description

CaSR biased allosteric modulator

AC 265347 is a CaSR biased allosteric modulator (pEC50 = 7.8-8.1). Calcimimetic. Displays ability to bias signalling towards the accumulation of pERK1/2 and IP1. Reduces parathyroid hormone (PTH) levels in rat serum without inducing the release of calcitonin. Exhibits no significant activation of human GABAB or type I PTH receptors. Orally active.
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Specifications

Chemical Name or Material α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol
CAS 1253901-26-6
Assay Percent Range >99%
Quantity 10 mg
Molecular Formula C17H17NOS
Formula Weight Observed MW: 283.39
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