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  8. A 839977, MedChemExpress

A 839977, MedChemExpress

Product Code. 16495928
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Product Code. 16495928 Supplier Medchem Express Supplier No. HY13954

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Description

MedChemExpress A 839977 is a P2X7 selective antagonist; it blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20 nM, 42 nM and 150 nM respectively) and reduces inflammatory and neuropathic pain in animal models; the antihyperalgesic effects of P2X7 receptor blockade are mediated by blocking the release of IL-1beta.

A 839977 is a P2X7 selective antagonist

Specifications

Chemical Name or Material A 839977
CAS 870061-27-1
Color White
Purity Grade Notes Research
Molecular Formula C19H14Cl2N6O
Quantity 10 mg
Solubility Information DMSO : ≥ 100 mg/mL (241.98 mM)
SMILES ClC1=C(Cl)C(N2N=NN=C2NCC3=CC=CC=C3OC4=NC=CC=C4)=CC=C1
Molecular Weight (g/mol) 413.26
Formula Weight 413.26
Percent Purity 98.01%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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