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4-Iodobenzoyl chloride, 98%
Description
4-Iodobenzoyl chloride is employed in the preparation of pyrroles by reaction with imines and acetylenes mediated by isocyanides using palladium catalysis. It is also used in the preparation of N-(1-benzylpyrrolidin-3-yl)arylbenzamides, potential human dopamine D4 antagonists. Further, it is used to prepare [2]rotaxane monomer and poly[2] rotaxane. In addition to this, it is important in the modification of poly(allylamine) in order to make the polymer X-ray visible.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
4-Iodobenzoyl chloride is employed in the preparation of pyrroles by reaction with imines and acetylenes mediated by isocyanides using palladium catalysis. It is also used in the preparation of N-(1-benzylpyrrolidin-3-yl)arylbenzamides, potential human dopamine D4 antagonists. Further, it is used to prepare [2]rotaxane monomer and poly[2] rotaxane. In addition to this, it is important in the modification of poly(allylamine) in order to make the polymer X-ray visible.
Solubility
Soluble in toluene and benzene.
Notes
Moisture sensitive. Incompatible with strong bases and water.
Specifications
Specifications
| Melting Point | 61°C to 65°C |
| Boiling Point | 120°C to 121°C (1 mmHg) |
| Flash Point | >110°C (230°F) |
| Quantity | 5 g |
| UN Number | UN3261 |
| Beilstein | 774718 |
| Sensitivity | Light and moisture sensitive |
| Solubility Information | Soluble in toluene and benzene. |
| Formula Weight | 266.47 |
| Percent Purity | 98% |
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Safety and Handling
- 4-Iodobenzoyl chloride
- Danger
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 B
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : 4-Iodobenzoyl chloride
RUO – Research Use Only
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