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Alfa Aesar™ 3-Bromopropionyl chloride, tech. 90%
Description
Applications
3-Bromopropionyl chloride acts as an acrylate synthon by reaction with 2-oxazolidinone, followed by base-promoted elimination to form a Diels-Alder dienophile. Brominated poly (ethylene glycol) methacrylate (v-PEG-Br) which was synthesized by the reaction of poly (ethyleneglycol) methacrylate, v-PEG-OH with Mn = 526 Dalton and 3-bromopropionyl chloride. Used in the reduction of organic compounds by mixed hydrides. Used as reagent in Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists. Reaction of veratrole with 3- bromopropionyl chloride led to the formation of 15 in 82% yield, which on treatment with the Tebbe reagent13 led to the formation of styryl bromide 16 in 93% yield. Used in the preparation of ome new mono- and di-nitrogen-containing monobenzo-crowns. 3-Bromopropionyl chloride was used in the preparation of 1-chloro-4-bromo-2-butanone.
Solubility
Reacts with water.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture, bases.
3-Bromopropionyl chloride acts as an acrylate synthon by reaction with 2-oxazolidinone, followed by base-promoted elimination to form a Diels-Alder dienophile. Brominated poly (ethylene glycol) methacrylate (v-PEG-Br) which was synthesized by the reaction of poly (ethyleneglycol) methacrylate, v-PEG-OH with Mn = 526 Dalton and 3-bromopropionyl chloride. Used in the reduction of organic compounds by mixed hydrides. Used as reagent in Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists. Reaction of veratrole with 3- bromopropionyl chloride led to the formation of 15 in 82% yield, which on treatment with the Tebbe reagent13 led to the formation of styryl bromide 16 in 93% yield. Used in the preparation of ome new mono- and di-nitrogen-containing monobenzo-crowns. 3-Bromopropionyl chloride was used in the preparation of 1-chloro-4-bromo-2-butanone.
Solubility
Reacts with water.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture, bases.
Specifications
Specifications
| Boiling Point | 54°C to 56°C (14 mmHg) |
| Flash Point | 79°C (174°F) |
| Quantity | 100 g |
| UN Number | UN3265 |
| Beilstein | 605453 |
| Formula Weight | 171.43 |
| Percent Purity | 90% |
| Grade | Technical |
| Chemical Name or Material | 3-Bromopropionyl chloride |
Product Title
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