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  6. TdB Labs AB 10 kDa FITC-DEAE-dextran Green Fluorophore

TdB Labs AB 10 kDa FITC-DEAE-dextran Green Fluorophore

Product Code. 30216347
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Quantity:
100 mg
1 g
Unit Size:
100mg
1g
This item is not returnable. View return policy

Product Code. 30216347

Brand: TdB Labs AB FDD10_100mg

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This item is not returnable. View return policy

Description

FITC-DEAE-dextran 10 kDa is a green-fluorescent, cationic tracer used in nucleic acid delivery, transfection studies, and charge-based interaction assays. Its positive charge supports electrostatic complex formation.

  • Product Overview: FITC-DEAE-dextrans are diethylaminoethyl-modified dextrans conjugated with fluorescein isothiocyanate (FITC), providing a green-fluorescent, cationic polysaccharide ideal for studies of electrostatic interactions, molecular complexation, and cellular uptake. Their positive charge, combined with bright fluorescence, makes FITC-DEAE-dextrans valuable tools in cell biology, drug delivery research, and membrane permeability studies.
  • Features:
    • Stable Green Fluorescence: Excitation at 495 nm and emission at 519 nm, compatible with standard FITC detection systems.
    • Positive Surface Charge: DEAE-modification imparts a strong cationic character, supporting binding to negatively charged membranes, proteins, and nucleic acids.
    • Water-Soluble and Biocompatible: Soluble in aqueous solutions, ready for immediate use in biological experiments.
    • Available in Multiple Molecular Weights: Offered in different sizes to suit applications involving cellular transport, binding studies, and permeability analysis.
    • Controlled Labeling: Manufactured under tight specifications to maintain optimal fluorescence intensity and reproducibility between batches.
  • Benefits:
    • Supports Cellular Uptake Studies: Cationic charge enhances uptake by endocytosis, useful for modeling drug delivery and nanoparticle entry into cells.
    • Ideal for Electrostatic Binding Research: Facilitates investigation of interactions between positively charged polymers and anionic biological targets.
    • Useful in Membrane Permeability Models: Applied to study transport and binding behavior at biological barriers, including epithelial and endothelial layers.
    • Bright and Reliable Detection: FITC labeling provides a strong, standardized signal suitable for microscopy, flow cytometry, and plate-based assays.
    • Flexible Application Range: Used across research fields including cell biology, biophysics, drug delivery, and materials science.
  • Applications:
    • Cellular Uptake and Endocytosis Studies: Traces the internalization pathways of cationic macromolecules in live cells.
    • Electrostatic Interaction Studies: Used to model binding between charged biomolecules and surfaces.
    • Barrier Permeability Research: Assesses transport behavior across polarized cell layers and tissue models.
    • Drug Delivery System Modeling: Simulates the behavior of cationic carriers in biological systems for targeted delivery applications.
    • Surface Coating and Modification Studies: Investigates how positively charged molecules interact with functionalized materials and biosurfaces.
  • Technical Specifications:
    • Fluorescence: Excitation maximum at 495 nm, emission maximum at 519 nm.
    • Molecular Weights: Available in standard dextran sizes modified with DEAE groups; specific molecular weights tailored to application needs.
    • Appearance: Light-sensitive, greenish dry powder, readily soluble in water.
    • Charge Density: Strong positive charge due to DEAE functionalization supporting binding to anionic targets.
  • Storage and Stability:
    • Store dry, protected from light, at 2°C to 8°C to maintain fluorescence and functionality.
    • Stable under recommended conditions for extended storage without significant loss of performance.
  • Packaging and Availability:
    • Supplied as dry powder for long-term stability and ease of handling.
    • Available in a variety of pack sizes to support both small research projects and larger studies.

Specifications

Quantity 100 mg
Product Type Fluorescent Labeling Reagent
Molecular Weight (g/mol) 10 kDa
Label Type Other Labels or Dyes
Color Green
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