CAS RN 939981-39-2

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RG7112, MedChemExpress

MedChemExpress RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2.

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Specifications

Molecular Weight (g/mol)	727.78
Color	White
Physical Form	Solid
Chemical Name or Material	RG7112
Grade	Research
SMILES	C[C@@]1([C@](C)(N(C(C2=CC=C(C=C2OCC)C(C)(C)C)=N1)C(N3CCN(CC3)CCCS(=O)(C)=O)=O)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.84%
CAS	939981-39-2
Solubility Information	DMSO : 200 mg/mL (274.81 mM; Need ultrasonic)
Synonym	RO5045337
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₈H₄₈Cl₂N₄O₄S
Formula Weight	727.78

CAS RN 939981-39-2

CAS RN 939981-39-2

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