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CAS RN 778277-15-9

ONHOHNNNHOFFF

CAS RN 778277-15-9

IUPAC Name: N-(2-hydroxyethyl)-3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide
Synonyms: N-(2-hydroxyethyl)-3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide
Molecular Weight (g/mol): 418.38
Molecular Formula: C20H17F3N4O3
InChi Key: IIQUYGWWHIHOCF-UHFFFAOYSA-N
SMILES: OCCNC(=O)C1=CC=CC(=C1)C1=CC(NC2=CC=C(OC(F)(F)F)C=C2)=NC=N1
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Tocris Bioscience™ GNF 5
GREENER_CHOICE

CAS: 778277-15-9 Molecular Formula: C20H17F3N4O3

CAS 778277-15-9
Molecular Formula C20H17F3N4O3
3

GNF-5, MedChemExpress

MedChemExpress GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22±0.1 uM (Wild type Abl).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 418.37
Color White
Physical Form Solid
Chemical Name or Material GNF-5
Grade Research
SMILES FC(F)(F)OC(C=C1)=CC=C1NC2=NC=NC(C3=CC=CC(C(NCCO)=O)=C3)=C2
For Use With (Application) Cancer-Kinase/protease
Percent Purity 99.42%
CAS 778277-15-9
Solubility Information DMSO : ≥ 49 mg/mL (117.12 mM)
Health Hazard 1 H301∣H319
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C20H17F3N4O3
Formula Weight 418.37