CAS RN 592542-59-1

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Rigosertib, MedChemExpress

MedChemExpress Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.

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Specifications

Molecular Weight (g/mol)	451.49
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Rigosertib
Grade	Research
SMILES	COC1=CC=C(C=C1NCC(O)=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O.[(E)]
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	592542-59-1
Solubility Information	DMSO : 75 mg/mL (166.12 mM; Need ultrasonic)
Synonym	ON-01910
Purity Grade Notes	Research
Recommended Storage	-20°C, stored under nitrogen∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	-20°C, stored under nitrogen∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₂₁H₂₅NO₈S
Formula Weight	451.49

CAS RN 592542-59-1

CAS RN 592542-59-1

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