CAS RN 575474-82-7

IUPAC Name: —

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MedChemExpress R112 is an ATP-competitive inhibitor of Syk kinase with a Ki of 96 nM. R112 inhibits Syk kinase activity with an IC50 of 226 nM.

Molecular Weight (g/mol)	312.3
Color	Yellow
Physical Form	Solid
Chemical Name or Material	R112
Grade	Research
SMILES	FC1=CN=C(NC2=CC(O)=CC=C2)N=C1NC3=CC(O)=CC=C3
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.23%
CAS	575474-82-7
Solubility Information	DMSO : 55 mg/mL (176.11 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₆H₁₃FN₄O₂
Formula Weight	312.3