CAS RN 1599440-33-1

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Dxd, MedChemExpress

MedChemExpress Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

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Specifications

Molecular Weight (g/mol)	493.48
Color	Off-White
Physical Form	Powder
Chemical Name or Material	Dxd
Grade	Research
SMILES	O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.02%
CAS	1599440-33-1
Solubility Information	DMSO : 7.14 mg/mL (14.47 mM; Need ultrasonic)
Synonym	Exatecan derivative for ADC
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₆H₂₄FN₃O₆
Formula Weight	493.48

CAS RN 1599440-33-1

CAS RN 1599440-33-1

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