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CAS RN 1448428-04-3

CAS RN 1448428-04-3

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Selonsertib, MedChemExpress

MedChemExpress Selonsertib (GS-4997), an orally bioavailable, selective apoptosis signal-regulating kinase 1 (ASK1) inhibitor with a pIC50 of 8.3, has been evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 445.49
Color Light Yellow
Physical Form Solid
Chemical Name or Material Selonsertib
Grade Research
SMILES O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F
For Use With (Application) Cancer-Kinase/protease
Percent Purity 96.8%
CAS 1448428-04-3
Solubility Information DMSO : ≥ 31 mg/mL (69.59 mM)
Synonym GS-4997
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C24H24FN7O
Formula Weight 445.49