CAS RN 1421373-98-9

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AZ-5104, MedChemExpress

MedChemExpress AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	485.58
Color	Yellow
Physical Form	Solid
Chemical Name or Material	AZ-5104
Grade	Research
SMILES	C=CC(NC1=CC(NC2=NC=CC(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.34%
CAS	1421373-98-9
Solubility Information	DMSO : ≥ 28 mg/mL (57.66 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₃₁N₇O₂
Formula Weight	485.58

CAS RN 1421373-98-9

CAS RN 1421373-98-9

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