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Zimlovisertib, MedChemExpress

Product Code. 16487736
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Product Code. 16487736

Brand: Medchem Express HY19836

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Description

MedChemExpress Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.

Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.

Specifications

Chemical Name or Material Zimlovisertib
CAS 1817626-54-2
Color Light Nude
Purity Grade Notes Research
Molecular Formula C18H20FN3O4
Quantity 100 mg
Synonym PF-06650833
Solubility Information DMSO : 62.5 mg/mL (172.95 mM; ultrasonic and warming and heat to 60°C)
SMILES NC(C1=C(OC)C=C2C(C=CN=C2OC[C@@H]3[C@H](CC)[C@H](F)C(N3)=O)=C1)=O
Molecular Weight (g/mol) 361.37
Formula Weight 361.37
Percent Purity 99.7%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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