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Invitrogen™ Human Klotho ELISA Kit

Product Code. 30245037
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:
96 Tests
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Product Code. 30245037

Brand: Invitrogen™ EEL200

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This item is not returnable. View return policy

ELISA

KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9UEF7
Assay Range 0.31 to 20 ng/mL
Assay Sensitivity 0.19 ng/mL
Conjugate HRP
Detection Method Colorimetric
Immunoassay Kit Format ELISA Microplate (Dismountable)
Product Type ELISA
Sample Type Plasma, Serum
Target Species Human
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 9365
Gene Symbol KL
Interassay CV <10
Intraassay CV <10
Kit Contents Micro ELISA Plate (Dismountable), Reference Standard, Concentrated Biotinylated Detection Ab(100x), Concentrated HRP Conjugate (100x), Reference Standard & Sample Diluent, Biotinylated Detection Ab Diluent, HRP Conjugate Diluent, Concentrated Wash Buffer(25x), Substrate Reagent, Stop Solution, Plate Sealer, Product Description, Certificate of Analysis
Label or Dye Biotin
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma: 100 μL, Serum: 100 μL
Storage Requirements Refer to product documentation for component specific storage temperature.
Target Klotho
Test Time 1 hr. 20 min.
Total Assay Time 3 hr. 30 min.
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