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Invitrogen™ Human Klotho ELISA Kit
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96 Tests
Description
KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Specifications
Specifications
| Accession Number | Q9UEF7 |
| Assay Range | 0.31 to 20 ng/mL |
| Assay Sensitivity | 0.19 ng/mL |
| Conjugate | HRP |
| Detection Method | Colorimetric |
| Immunoassay Kit Format | ELISA Microplate (Dismountable) |
| Product Type | ELISA |
| Sample Type | Plasma, Serum |
| Target Species | Human |
| For Use With (Equipment) | Colorimetric Microplate Reader |
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