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X-376, MedChemExpress

Product Code. p-200096679
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Product Code. 16497088

Brand: Medchem Express HY16590

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Description

MedChemExpress X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM). X-376 is a less potent inhibitor of MET (IC50=0.69 nM). X-376 displays potent anti-tumor activity.

X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM). X-376 is a less potent inhibitor of MET (IC50=0.69 nM). X-376 displays potent anti-tumor activity.

Specifications

Chemical Name or Material X-376
CAS 1365267-27-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C25H25Cl2FN6O3
Quantity 10 mg
Solubility Information DMSO : 100 mg/mL (182.68 mM; Need ultrasonic)
SMILES O=C(C1=NN=C(N)C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1)NC3=CC=C(C(N4CCN(C)CC4)=O)C=C3
Molecular Weight (g/mol) 547.41
Formula Weight 547.41
Percent Purity 98.37%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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