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  7. WYE-687, MedChemExpress

WYE-687, MedChemExpress

Product Code. 16482517
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Product Code. 16482517 Supplier Medchem Express Supplier No. HY15271

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Description

MedChemExpress WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.

WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.

Specifications

Chemical Name or Material WYE-687
CAS 1062161-90-3
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C28H32N8O3
Quantity 50 mg
Solubility Information DMSO : 20.83 mg/mL (39.41 mM; ultrasonic and warming and heat to 80°C)
SMILES O=C(OC)NC1=CC=C(C2=NC(N3CCOCC3)=C4C(N(C5CCN(CC6=CC=CN=C6)CC5)N=C4)=N2)C=C1
Molecular Weight (g/mol) 528.61
Formula Weight 528.61
Percent Purity 98.1%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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