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  7. WYE-354, MedChemExpress

WYE-354, MedChemExpress

Product Code. p-200100217
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16457677 5 mg 5mg
16434938 10 mg 10mg
16401187 50 mg 50mg
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Product Code. 16457677 Supplier Medchem Express Supplier No. HY120345mg

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Description

MedChemExpress WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro.

WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro.

Specifications

Chemical Name or Material WYE-354
CAS 1062169-56-5
Color White
Purity Grade Notes Research
Molecular Formula C24H29N7O5
Quantity 5 mg
Solubility Information DMSO : 6.67 mg/mL (13.46 mM; Need ultrasonic)
SMILES COC(NC1=CC=C(C=C1)C2=NC3=C(C(N4CCOCC4)=N2)C=NN3C5CCN(CC5)C(OC)=O)=O
Molecular Weight (g/mol) 495.53
Formula Weight 495.53
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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