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Gibco™ Human IL-12 p80 Recombinant Protein, PeproTech®

Product Code. 17891593
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Quantity:
10 μg
10 x 100 μg
100 μg
2 μg
2.5 x 100 μg
5 x 100 μg
50 μg
Unit Size:
100µg
10µg
1mg
250µg
2µg
500µg
50µg
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Product Code. Quantity unitSize
17891593 10 μg 10µg
17890213 10 x 100 μg 1mg
17860213 100 μg 100µg
30088438 2.5 x 100 μg 250µg
30088762 5 x 100 μg Pack of 5
17860423 2 μg 2µg
17871593 2.5 x 100 μg 250µg
17870823 5 x 100 μg 500µg
17850593 50 μg 50µg
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Product Code. 17891593 Supplier Gibco™ Supplier No. 20012P80H10UG

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This item is not returnable. View return policy

Description

Recombinant Protein

200-12P80H-1MG will be provided as 10 x 100 μg (200-12P80H-100UG). 200-12P80H-250UG will be provided as multiple 50 μg (200-12P80H-50UG) and 100 μg (200-12P80H-100UG) vials. 200-12P80H-500UG will be provided as 5 x 100 μg (200-12P80H-100UG). Recombinant Human IL-12 p80 is an 80.0 kDa disulfide linked homodimer consisting of two p40 chains of IL-12. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicates that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or it can form the homodimer designated IL-12 p80. Elevated levels of IL-12 p80 correlate to macrophage recruitment and increased inflammation in asthma and respiratory viral infection models.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P29460
For Use With (Application) Control
Formulation Protein with no preservative
Gene ID (Entrez) 3593
Molecular Weight (g/mol) 80 kDa
Name Human IL-12 p80
Purification Method Purified
Quantity 10 μg
Source Insect cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias IL-12; Interleukin
Common Name IL-12 p80
Gene Symbol IL12B
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence p40 subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS
Content And Storage -20°C
Expression System Insect cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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