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Upadacitinib, MedChemExpress

Product Code. 16473767
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Product Code. 16473767

Brand: Medchem Express HY19569

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Description

MedChemExpress Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.

Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.

Specifications

Chemical Name or Material Upadacitinib
Physical Form Powder
CAS 1310726-60-3
Color Gray
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C17H19F3N6O
For Use With (Application) COVID-19-immunoregulation
Synonym ABT-494
Solubility Information DMSO : ≥ 22 mg/mL (57.84 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F
Molecular Weight (g/mol) 380.37
Formula Weight 380.37
Percent Purity 98.56%
Grade Research
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Research purposes only

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