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UNC0646, MedChemExpress

Product Code. 16498517
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Product Code. 16498517 Supplier Medchem Express Supplier No. HY13807

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Description

MedChemExpress UNC0646 is a potent and selective histone methyltransferase G9a inhibitor with an IC50 of 6 nM. UNC0646 is also a potent GLP inhibitor (IC50 G9a/GLP over SETD7, SUV39H2, SETD8 and PRMT3. UNC0646 reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 26 nM.

UNC0646 is a potent and selective histone methyltransferase G9a inhibitor with an IC50 of 6 nM. UNC0646 is also a potent GLP inhibitor (IC50 G9a/GLP over SETD7, SUV39H2, SETD8 and PRMT3. UNC0646 reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 26 nM.

Specifications

Chemical Name or Material UNC0646
CAS 1320288-17-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C36H59N7O2
Quantity 5 mg
Solubility Information DMSO : 50 mg/mL (80.40 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 80°C)
SMILES COC1=CC2=C(NC3CCN(C4CCCCC4)CC3)N=C(N5CCN(C(C)C)CCC5)N=C2C=C1OCCCN6CCCCC6
Molecular Weight (g/mol) 621.9
Formula Weight 621.9
Percent Purity 99.13%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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