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DiscoverX U2OS GRM5 Gq Cell Line
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Quantity:
2 Vials
Unit Size:
2 ampoules
Description
The GRM5 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. L-glutamate) based activation of GRM5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GRM5 , a naturally Gq coupled GPCR. Upon activation of GRM5 , the resulting calcium activity can be fluorescently assayed using the Calcium NoWash PLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells.
Specifications
Specifications
| Assay Entry | Calcium Signaling |
| Cell Line | U2OS |
| For Use With (Application) | Cell Lines |
| Primary Agonist | L-Glutamate |
| Quantity | 2 Vials |
| Target Entry | GRM5 |
| Accession Number | NM_000842.3 |
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