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Tofogliflozin (hydrate), MedChemExpress

Product Code. 16485668
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Product Code. 16485668 Supplier Medchem Express Supplier No. HY13413

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Description

MedChemExpress Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2. Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells.

Specifications

Chemical Name or Material Tofogliflozin (hydrate)
CAS 1201913-82-7
Color White
Purity Grade Notes Research
Molecular Formula C22H28O7
Quantity 10 mg
Synonym CSG-452 hydrate
Solubility Information DMSO : ≥ 100 mg/mL (247.25 mM) ∣H2O : 0.33 mg/mL (0.82 mM; Need ultrasonic)
SMILES O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O
Molecular Weight (g/mol) 404.45
Formula Weight 404.45
Percent Purity 98.73%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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