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Invitrogen™ TNFRSF14 (HVEM) Recombinant Rabbit Monoclonal Antibody (BLR062G)

Rabbit Recombinant Monoclonal Antibody
148.00 EUR - 452.00 EUR
Specifications
| Antigen | TNFRSF14 (HVEM) |
|---|---|
| Clone | BLR062G |
| Concentration | 1 mg/mL |
| Content And Storage | 4°C |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17735689
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Invitrogen™
MA544317 |
100 μL |
452.00 EUR
100µL |
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|
17745689
|
Invitrogen™
MA544318 |
10 μL |
148.00 EUR
10µL |
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Description
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
TNFRSF14 is a member of the TNF-receptor superfamily. TNFRSF14 was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 has been shown to be part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Activation of the signal transduction pathway involving TNFRSF14 in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these TNFRSF14 variants have not been determined.Specifications
| TNFRSF14 (HVEM) | |
| 1 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| BBS with 0.09% sodium azide; pH 8.2 | |
| Q92956 | |
| 8764 | |
| Recombinant protein representing the extracellular domain of human TNF receptor superfamily member 14, transcript variant 1 (Herpesvirus entry mediator A, HVEM) (residues 39-200). | |
| Antibody |
| BLR062G | |
| 4°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human | |
| TNFRSF14 | |
| Atar; CD270; CD40-like protein; herpes virus entry mediator; herpes virus entry mediator A; Herpesvirus entry mediator A; HGNC:11912; HVEA; Hvem; LIGHTR; RP3-395M20.6; sCD2710; TNF receptor superfamily member 14; Tnfrs14; TNFRSF14; TR2; tumo; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; UNQ329/PRO509 | |
| TNFRSF14 | |
| Primary | |
| Purified |
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