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Tivozanib, MedChemExpress

Product Code. p-200099685
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Product Code. 16490647

Brand: Medchem Express HY10977

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Description

MedChemExpress Tivozanib (AV-951; KRN951) is a potent and selective and orally active VEGFR tyrosine kinase inhibitor with IC50是of 0.21, 0.16, 0.24 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively. Tivozanib inhibits angiogenesis and vascular permeability in tumor tissues and shows antitumor activity. Tivozanib has the potential for the research of metastatic renal cell carcinoma (RCC) .

Tivozanib (AV-951

Specifications

Chemical Name or Material Tivozanib
CAS 475108-18-0
Color Brown
Purity Grade Notes Research
Molecular Formula C22H19ClN4O5
Quantity 50 mg
Synonym AV-951 KRN951
Solubility Information DMSO : 25 mg/mL (54.96 mM; Need ultrasonic)
SMILES O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4
Molecular Weight (g/mol) 454.86
Formula Weight 454.86
Percent Purity 99.37%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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