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Invitrogen™ TGIF Polyclonal Antibody
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Product Code. 15662625
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Quantity:
400 μL
Unit Size:
400µL
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Product Code. Quantity unitSize
15662625 400 μL 400µL
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Product Code. 15662625 Supplier Invitrogen™ Supplier No. PA548328

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Description

Rabbit Polyclonal Antibody

Predicted to react with chicken based on sequence homology.

TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TGIF
Applications Western Blot
Classification Polyclonal
Concentration 2.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene TGIF1
Gene Accession No. P70284, Q15583
Gene Alias 5'-TG-3'-interacting factor 1; AA959811; AI462167; Homeobox protein TGIF1; HPE4; TALE family homeobox; TALE homeobox TG-interacting factor; Tfig; TG interacting factor 1; TGFB induced factor homeobox 1; TGFB-induced factor homeobox 1; TGIF; Tgif1; transforming growth factor-beta-induced factor
Gene Symbols TGIF1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF1.
Purification Method Ammonium Sulfate Precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21815, 7050
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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