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Thermo Scientific™ Tango™ OPRD1-bla U2OS Cells

The Tango™ OPRD1 -bla U2OS cells contain the human Opioid Receptor Delta 1 (OPRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

Brand:  Thermo Scientific™ K1778

Product Code. 10667543

  • 12500.00 EUR / Each
Estimated Shipment: 26-11-2024
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Description

Description

The Tango™ OPRD1 -bla U2OS cells contain the human Opioid Receptor Delta 1 (OPRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ OPRD1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ OPRD1-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_000911.3
Dividing Cells
Native Tail
Fluorescence
OPRD1
Single Cell Clone Origin
GPCR (G-Protein Coupled Receptors)
End Point
U2OS
U2OS Cell
Tango™
Cell-based beta-arrestin recruitment
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ OPRD1-bla U2OS cells
• Tango™ OPRD1-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ OPRD1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Tango™ OPRD1-bla U2OS Cells, 8 x 106 Cells, U2OS Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage
Pharma and biopharma, drug discovery and development, target and lead identification and validation, G-protein coupled receptor biology, cell-based GPCR reporter assays
Tango™ OPRD1-bla U2OS cells (LiveBLAzer™-FRET B/G loading kit, solution D and other materials are required separately; please refer to the protocol). Includes: Tango™ OPRD1-bla U2OS cells, Tango™ OPRD1-bla U2OS assay protocol, certificate of analysis
GeneBLAzer™
8 x 106 Cells
BLA (Beta-Lactamase)
OPRD1
U2OS
GPCR
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For Research Use Only. Not for use in diagnostic procedures.